PCSK9 reloaded: sirtuin-1 as a post-translational checkpoint for LDL-C control
This editorial refers to ‘Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation’ by S. Velagapudi et al.
Read the full editorial (Cardiovascular Research (2025) 121, 1306–1307) here!