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The myth of Sisyphos and the route of cardiovascular medicine

Cheating death, is this not the mission of medicine, of physicians at large? Indeed, over the last 200 years we have reduced child and mother mortality massively, vaccinations have prevented fatal pandemics that had killed millions in the past such as polio and small pox and other viral diseases. 

Read the full article (European Heart Journal (2026) 00, 1–6) here!

DeepSTEMI: a step forward in automated cardiovascular risk prediction

ST-elevation myocardial infarction (STEMI) remains a formidable clinical challenge despite remarkable advances in reperfusion therapy...This work represents an important step towards automated, scalable risk stratification,but it remains an early proof of concept that needs validation in larger,more diverse cohorts and prospective studies.

Read full article (Science Bulletin 71 (2026) 4066–4068) here!

The MagMa Study: Quantum Magnetocardiography in Cardiomyopathy

Rapid diagnostic screening is an unmet need in patients with suspected cardiomyopathy (CM). The authors recently demonstrated in a retrospective study that magnetocardiography (MCG) may be a suitable tool to detect CM. This study aims to prospectively evaluate the accuracy of MCG as a screening tool in patients with suspected CM.

Read full article (JACC Heart Fail. 2026;14(8):103182) here!
 

Adrenomedullin system dysregulation predicts cardiogenic shock and mortality in acute coronary syndromes

Does the inclusion of markers of the adrenomedullin (ADM) system improve early prediction of cardiogenic shock and mortality
in initially stable patients with acute coronary syndromes (ACS)?

Read the full article (Eur Heart J. 2026;00:1–16) here!

Takotsubo syndrome diagnosis: the biomarker-based BioTAK score

Currently, takotsubo syndrome (TTS) is diagnosed based on clinical examination, medical, psychiatric, and neurological history, repeated cardiac imaging, and coronary angiography, leading to delayed diagnosis and potentially avoidable invasive procedures. Can biomarkers help the early differentiation of TTS from acute coronary syndrome (ACS)?

Read full article (Eur Heart J. 2026;00:1–14) here!
 

Cliramitug for depletion of cardiac amyloid transthyretin: long-term follow-up of the NI006-101 trial

In a first-in-human trial (NI006-101), the monoclonal antibody cliramitug, targeting misfolded transthyretin, demonstrated a favorable safety profile and time- and dose-dependent reductions in surrogate markers of cardiac amyloid burden over the course of 12 months in patients with amyloid transthyretin cardiomyopathy (ATTR-CM). 

Read full article ( Nat Med 2026 Jun 26) here!

A new definition of MINOCA: from infarction to injury

This new definition of MINOCA, replacing the ‘I’ for infarction with the ‘I’ for injury, better reflects the working diagnosis nature of this terminology, whilst also emphasizing the need for further invasive and non-invasive testing to identify the final diagnosis, which can be epicardial, microvascular, myocardial, and non-cardiac.

Read the full article (European Heart Journal (2026) 00, 1–4) here!

Safe Hearts Plan & visibility through the new ESC website

Cardiovascular disease remains Europe’s leading cause of death, and addressing this burden requires visibility, credibility and coordinated action. The new ESC website, www.escardio.org, is a strategic tool for the ESC to reinforce its role as a trusted scientific and public health partner at European and global level.

Read full article (ESC Officers Newsletter- Issue 3, Summer 2026) here!

European Society of Cardiology: cardiovascular disease statistics 2025

This 2025 report from the ESC Atlas project is the fifth in a biennial series. It presents and compares updated cardiovascular disease (CVD) statistics for more than 50 of the ESC member countries. 

Read full article (European Heart Journal (2026) 00, 1–45) here!

Environmental risk factors and cardiovascular health

The article outlines urgent research needs, such as the need for high-resolution exposure data, exploration of gene–environment interactions and molecular pathways, and the development of real-world and mechanistic studies assessing interventions. 

Read full article (European Heart Journal (2026) 00, 1–25) here!