International Takotsubo Registry
Takotsubo cardiomyopathy (TTC) also known as stress cardiomyopathy or broken heart syndrome was first described in Japan in 1990. In Japanese, “tako-tsubo” means “octopus pot”, which describes the shape of the ventricle during systole. The clinical presentation of TTC mimics the Acute Coronary Syndrome (ACS), including sudden onset of chest pain, ST-segment elevation and in some instances elevated cardiac enzymes. Coronary angiography is the gold standard diagnostic test to exclude coronary artery stenosis. Left ventricular-angiography often reveals a systolic dysfunction and wall motion abnormality [cf. video], which in most cases are reversible once the acute phase passes. The overall prognosis is favorable however, in the acute phase TTC is a life-threatening condition with a similar mortality rate as ACS. Thus, correct diagnosis and prompt management are essential, TTC most predominantly affects postmenopausal women after a stressful event; however it can also affect men. Currently, the exact etiology and pathophysiology of TTC are not well understood.
Project leader: PD Dr. med. Dr. rer. nat. Christian Templin (on the right), attending physician interventional cardiology and acute cardiac care.
For more information on the International Takotsubo Registry visit the website www.takotsubo-registry.com. Furthermore, we like to encourage other cardiovascular centers and hospitals to participate in the registry.