Selected Publications 2015 - 2022
Selected Original Research 2015 - 2022
Yang K, Velagapudi S, Akhmedov A, Kraler S, Lapikova-Bryhinska T, Schmiady MO, Wu X, Geng L, Camici GG, Xu A, Lüscher TF. Cardiovasc. Res. 2023; in press.
Sex-specific evaluation and redevelopment of the GRACE score in non-ST-segment eleva-tion acute coronary syndromes in populations from the UK and Switzerland: a multinational analysis with external cohort validation. Wenzl FA, Kraler S, Ambler G, Weston C, Herzog SA, Räber L, Olivier Muller, Giovanni G Camici, Marco Roffi, Hans Rickli, Keith A A Fox, Mark de Belder, Radovanovic D, Deanfield J, Lüscher TF. Lancet 2022; August 29 online.
Mammalian Target of Rapamycin Inhibition in Patients With ST-Segment Elevation Myocardial Infarction. Stähli BE , Klingenberg R, Heg D, Branca M, Manka R, Kapos I, Müggler O, Denegri A, Kesterke R, Berger F, Stehli J, Candreva A, von Eckardstein A, Carballo D, Hamm C, Landmesser U, Mach F, Moccetti T, Jung C, Kelm M, Münzel T, Pedrazzini G, Räber L, Windecker S, Templin C, Matter CM, Lüscher TF, Ruschitzka F. Mammalian Target of Rapamycin Inhibition in Patients With ST-Segment Elevation Myocardial Infarction. J. Am. Coll. Cardiol. 2022;80:1802-1814.
Lifelong dietary omega-3 fatty acid suppresses thrombotic potential through gut microbiota alteration in aged mice. Saeedi Saravi SS, Bonetti NR, Pugin B, Constancias F, Pasterk L, Gobbato S, Akhmedov A, Liberale L, Lüscher TF, Camici GG, Beer JH. iScience. 2021 Jul 22;24(8):102897. doi: 10.1016/j.isci.2021.102897. PMID: 34401676; PMCID: PMC8355916.
Twitter promotion is associated with higher citation rates of cardiovascular articles: the ESC Journals Randomized Study. Ladeiras-Lopes R, Vidal-Perez R, Santos-Ferreira D, Alexander M, Baciu L, Clarke S, Crea F, Lüscher TF. Eur Heart J. 2022 May 14;43(19):1794-1798. doi: 10.1093/eurheartj/ehac150. PMID: 35567549.
The BET Protein Inhibitor Apabetalone Rescues Diabetes-Induced Impairment of Angiogenic Response by Epigenetic Regulation of Thrombospondin-1. Mohammed SA, Albiero M, Ambrosini S, Gorica E, Karsai G, Caravaggi CM, Masi S, Camici GG, Wenzl FA, Calderone V, Madeddu P, Sciarretta S, Matter CM, Spinetti G, Lüscher TF, Ruschitzka F, Costantino S, Fadini GP, Paneni F. Antioxid Redox Signal. 2022 Apr;36(10-12):667-684. doi: 10.1089/ars.2021.0127. Epub 2022 Apr 1. PMID: 34913726.
Soluble lectin-like oxidized low-density lipoprotein receptor-1 predicts premature death in acute coronary syndromes. Kraler S, Wenzl FA, Georgiopoulos G, Obeid S, Liberale L, von Eckardstein A, Muller O, Mach F, Räber L, Losdat S, Schmiady MO, Stellos K, Stamatelopoulos K, Camici GG, Srdic A, Paneni F, Akhmedov A, Lüscher TF. Eur Heart J. 2022 Mar 24:ehac143. doi: 10.1093/eurheartj/ehac143. Epub ahead of print. PMID: 35325132.
Cardiorenal Risk of Celecoxib compared to Naproxen, or Ibuprofen in Arthritis Patients: Insights from the PRECISION trial. Obeid S, Libby P, Husni E, Wang Q, Wisniewski LM, Davey DA, Wolski KE, Xia F, Bao W, Walker C, Ruschitzka F, Nissen SE, Lüscher TF. Eur Heart J Cardiovasc Pharmacother. 2022 Mar 2:pvac015. doi: 10.1093/ehjcvp/pvac015. Epub ahead of print. PMID: 35234840.
Dietary alpha-linolenic acid reduces platelet activation and collagen-mediated cell adhesion in sickle cell disease mice. Stivala S, Gobbato S, Bonetti N, Camici GG, Lüscher TF, Beer JH. J Thromb Haemost. 2022 Feb;20(2):375-386. doi: 10.1111/jth.15581. Epub 2021 Dec 1. PMID: 34758193.
TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies. Akhmedov A, Crucet M, Simic B, Kraler S, Bonetti NR, Ospelt C, Distler O, Ciurea A, Liberale L, Jauhiainen M, Metso J, Miranda M, Cydecian R, Schwarz L, Fehr V, Zilinyi R, Amrollahi-Sharifabadi M, Ntari L, Karagianni N, Ruschitzka F, Laaksonen R, Vanhoutte PM, Kollias G, Camici GG, Lüscher TF. Cardiovasc Res. 2022 Jan 7;118(1):254-266. doi: 10.1093/cvr/cvab005. PMID: 33483748.
Cardiovascular Risk Profile, Presentation and Management Outcomes of Patients with Acute Coronary Syndromes after Coronary Artery Bypass Grafting. Mahmoud SES, Shahin M, Yousif N, Denegri A, Abo Dahab LH, Lüscher TF. Curr Probl Cardiol. 2021 Dec 11:101078. doi: 10.1016/j.cpcardiol.2021.101078. Epub ahead of print. PMID: 34902394.
Improving 1-year mortality prediction in ACS patients using machine learning. Weichwald S, Candreva A, Burkholz R, Klingenberg R, Räber L, Heg D, Manka R, Gencer B, Mach F, Nanchen D, Rodondi N, Windecker S, Laaksonen R, Hazen SL, von Eckardstein A, Ruschitzka F, Lüscher TF, Buhmann JM, Matter CM. Eur Heart J Acute Cardiovasc Care. 2021 Oct 27;10(8):855-865. doi: 10.1093/ehjacc/zuab030. PMID: 34015112; PMCID: PMC8557454.
Cysteine-Rich Angiogenic Inducer 61 Improves Prognostic Accuracy of GRACE (Global Registry of Acute Coronary Events) 2.0 Risk Score in Patients with Acute Coronary Syndromes. Klingenberg R, Aghlmandi S, Räber L, Akhmedov A, Gencer B, Carballo D, Nanchen D, Bucher HC, Rodondi N, Mach F, Windecker S, Landmesser U, von Eckardstein A, Hamm CW, Lüscher TF, Matter CM. J Am Heart Assoc. 2021 Oct 19;10(20):e020488. doi: 10.1161/JAHA.120.020488. Epub 2021 Oct 8. PMID: 34622666; PMCID: PMC8751861.
MMP-2 knockdown blunts age-dependent carotid stiffness by decreasing elastin degradation and augmenting eNOS activation. Diaz-Canestro C, Puspitasari YM, Liberale L, Guzik TJ, Flammer AJ, Bonetti NR, Wüst P, Costantino S, Paneni F, Akhmedov A, Varga Z, Ministrini S, Beer JH, Ruschitzka F, Hermann M, Lüscher TF, Sudano I, Camici GG.. Cardiovasc Res. 2021 Sep 29:cvab300. doi: 10.1093/cvr/cvab300. Epub ahead of print. PMID: 34586381.
Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis. Witkowski M, Witkowski M, Friebel J, Buffa JA, Li XS, Wang Z, Sangwan N, Li L, DiDonato JA, Tizian C, Haghikia A, Kirchhofer D, Mach F, Räber L, Matter CM, Tang WHW, Landmesser U, Lüscher TF, Rauch U, Hazen SL. Cardiovasc Res. 2021 Aug 5:cvab263. doi: 10.1093/cvr/cvab263. Epub ahead of print. PMID: 34352109.
Prognostic value of inflammatory biomarkers and GRACE score for cardiac death and acute kidney injury after acute coronary syndromes. Rossi VA, Denegri A, Candreva A, Klingenberg R, Obeid S, Räber L, Gencer B, Mach F, Nanchen D, Rodondi N, Heg D, Windecker S, Buhmann J, Ruschitzka F, Lüscher TF, Matter CM.. Eur Heart J Acute Cardiovasc Care. 2021 May 25;10(4):445-452. doi: 10.1093/ehjacc/zuab003. PMID: 33624028.
Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke. Bonetti NR, Liberale L, Akhmedov A, Pasterk L, Gobbato S, Puspitasari YM, Vukolic A, Saeedi Saravi SS, Coester B, Horvath C, Osto E, Montecucco F, Lüscher TF, Beer JH, Camici GG. Atherosclerosis. 2021 May;325:89-98. doi: 10.1016/j.atherosclerosis.2021.04.005. Epub 2021 Apr 20. PMID: 33915355.
A Novel Circulating MicroRNA for the Detection of Acute Myocarditis. Blanco-Domínguez R, Sánchez-Díaz R, de la Fuente H, Jiménez-Borreguero LJ, Matesanz-Marín A, Relaño M, Jiménez-Alejandre R, Linillos-Pradillo B, Tsilingiri K, Martín-Mariscal ML, Alonso-Herranz L, Moreno G, Martín-Asenjo R, García-Guimaraes MM, Bruno KA, Dauden E, González-Álvaro I, Villar-Guimerans LM, Martínez-León A, Salvador-Garicano AM, Michelhaugh SA, Ibrahim NE, Januzzi JL, Kottwitz J, Iliceto S, Plebani M, Basso C, Baritussio A, Seguso M, Marcolongo R, Ricote M, Fairweather D, Bueno H, Fernández-Friera L, Alfonso F, Caforio ALP, Pascual-Figal DA, Heidecker B, Lüscher TF, Das S, Fuster V, Ibáñez B, Sánchez-Madrid F, Martín P. N Engl J Med. 2021 May 27;384(21):2014-2027. doi: 10.1056/NEJMoa2003608. PMID: 34042389.
TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies. Akhmedov A, Crucet M, Simic B, Kraler S, Bonetti NR, Ospelt C, Distler O, Ciurea A, Liberale L, Jauhiainen M, Metso J, Miranda M, Cydecian R, Schwarz L, Fehr V, Zilinyi R, Amrollahi-Sharifabadi M, Ntari L, Karagianni N, Ruschitzka F, Laaksonen R, Vanhoutte PM, Kollias G, Camici GG, Lüscher TF. Cardiovasc Res. 2021 Jan 23:cvab005. doi: 10.1093/cvr/cvab005. Epub ahead of print. PMID: 33483748.
Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunD. Hussain S, Khan AW, Akhmedov A, Suades R, Costantino S, Paneni F, Caidahl K, Mohammed SA, Hage C, Gkolfos C, Björck H, Pernow J, Lund LH, Lüscher TF, Cosentino F. Circ Res. 2020 Oct 23;127(10):1261-1273. doi: 10.1161/CIRCRESAHA.120.317132. Epub 2020 Aug 20. PMID: 32815777.
COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England. Mafham MM, Spata E, Goldacre R, Gair D, Curnow P, Bray M, Hollings S, Roebuck C, Gale CP, Mamas MA, Deanfield JE, de Belder MA, Luescher TF, Denwood T, Landray MJ, Emberson JR, Collins R, Morris EJA, Casadei B, Baigent C. Lancet. 2020 Aug 8;396(10248):381-389. doi: 10.1016/S0140-6736(20)31356-8. Epub 2020 Jul 14. PMID: 32679111 Free PMC article.
Clinical Presentation and Laboratory Findings in Men Versus Women with Myocarditis. Patriki D, Kottwitz J, Berg J, Landmesser U, Lüscher TF, Heidecker B. J Womens Health (Larchmt). 2020 Feb;29(2):193-199. doi: 10.1089/jwh.2018.7618. Epub 2019 Aug 29. PMID: 31464553
Interleukin-1β Mediates Arterial Thrombus Formation via NET-Associated Tissue Factor. Liberale L, Holy EW, Akhmedov A, Bonetti NR, Nietlispach F, Matter CM, Mach F, Montecucco F, Beer JH, Paneni F, Ruschitzka F, Libby P, Lüscher TF, Camici GG. J Clin Med. 2019 Nov 26;8(12):2072. doi: 10.3390/jcm8122072. PMID: 31779200 Free PMC article.
Neurocardiology: the brain-heart connection in Takotsubo syndrome. Ghadri JR, Levinson RA, Lüscher TF, Jäncke L, Templin C. Eur Heart J. 2019 Sep 21;40(36):3062-3063. doi: 10.1093/eurheartj/ehz499. PMID: 31302668 No abstract available.
Macrophage NCOR1 protects from atherosclerosis by repressing a pro-atherogenic PPARγ signature. Oppi S, Nusser-Stein S, Blyszczuk P, Wang X, Jomard A, Marzolla V, Yang K, Velagapudi S, Ward LJ, Yuan XM, Geiger MA, Guillaumon AT, Othman A, Hornemann T, Rancic Z, Ryu D, Oosterveer MH, Osto E, Lüscher TF, Stein S. Eur Heart J. 2019 Sep 16. pii: ehz667.
Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes. Li XS, Obeid S, Wang Z, Hazen BJ, Li L, Wu Y, Hurd AG, Gu X, Pratt A, Levison BS, Chung YM, Nissen SE, Tang WHW, Mach F, Räber L, Nanchen D, Matter CM, Lüscher TF, Hazen SL. Eur Heart J. 2019 Aug 21;40(32):2700-2709.
Altered limbic and autonomic processing supports brain-heart axis in Takotsubo syndrome. Templin, C., Hänggi, J., Klein, C., Topka, M.S., Hiestand, T., Levinson, R.A., Jurisic, S., Lüscher, T.F., Ghadri, J.-R., Jäncke, L. Eur. Heart J 2019 Apr 14;40(15):1183-1187.
Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry. Gili, S., Cammann, V.L., Schlossbauer, S.A., Kato, K., D'Ascenzo, F., Vece, D.D., Jurisic, S., Micek, J., Obeid, S., Bacchi, B., Szawan, K.A., Famos, F., Sarcon, A., Levinson, R., Ding, K.J., Seifert, B., Lenoir, O., Bossone, E., Citro, R., Franke, J., Napp, L.C., Jaguszewski, M., Noutsias, M., Münzel, T., Knorr, M., Heiner, S., Katus, H.A., Burgdorf, C., Schunkert, H., Thiele, H., Bauersachs, J., Tschöpe, C., Pieske, B.M., Rajan, L., Michels, G., Pfister, R., Cuneo, A., Jacobshagen, C., Hasenfuß, G., Karakas, M., Koenig, W., Rottbauer, W., Said, S.M., Braun-Dullaeus, R.C., Banning, A., Cuculi, F., Kobza, R., Fischer, T.A., Vasankari, T., Airaksinen, K.E.J., Opolski, G., Dworakowski, R., MacCarthy, P., Kaiser, C., Osswald, S., Galiuto, L., Crea, F., Dichtl, W., Empen, K., Felix, S.B., Delmas, C., Lairez, O., El-Battrawy, I., Akin, I., Borggrefe, M., Gilyarova, E., Shilova, A., Gilyarov, M., Horowitz, J.D., Kozel, M., Tousek, P., Widimský, P., Winchester, D.E., Ukena, C., Gaita, F., Di Mario, C., Wischnew-sky, M.B., Bax, J.J., Prasad, A., Böhm, M., Ruschitzka, F., Lüscher, T.F., Ghadri, J.R., Templin, C. Eur Heart J 2019 Jul 1;40(26):2142-2151
Non-steroidal anti-inflammatory drug use in acute myopericarditis: 12-month clinical follow-up. Berg J, Lovrinovic M, Baltensperger N, Kissel CK, Kottwitz J, Manka R, Patriki D, Scherff F, Schmied C, Landmesser U, Lüscher TF, Heidecker B. Open Heart. 2019 Apr 3;6(1): e000990. doi: 10.1136/openhrt-2018-000990. eCollection 2019. PMID: 31168382 Free PMC article.
Obesity-induced activation of JunD promotes myocardial lipid accumulation and metabolic cardiomyopathy. Costantino, S., Akhmedov, A., Melina, G., Mohammed, S.A., Othman, A., Ambrosini, S., Wijnen, W.J., Sada, L., Ciavarella, G.M., Liberale, L., Tanner, F.C., Matter, C.M., Hornemann, T., Volpe, M., Mechta-Grigoriou, F., Camici, G.G., Sinatra, R., Lüscher, T.F., Paneni, F. Eur Heart J 2019 Mar 21;40(12):997-1008.
Takotsubo Recurrence: Morphological Types and Triggers and Identification of Risk Factors. Kato K, Di Vece D, Cammann VL, Micek J, Szawan KA, Bacchi B, Lüscher TF, Ruschitzka F, Ghadri JR, Templin C; InterTAK Collaborators.J Am Coll Cardiol. 2019 Mar 5;73(8):982-984. doi: 10.1016/j.jacc.2018.12.033. PMID: 30819368 No abstract available.
AP-1 (Activated Protein-1) Transcription Factor JunD Regulates Ischemia/Reperfusion Brain Damage via IL-1β (Interleukin-1β). Diaz-Cañestro, C., Reiner, M.F., Bonetti, N.R., Liberale, L., Merlini, M., Wüst, P., Amstalden, H., Briand-Schumacher, S., Semerano, A., Giacalone, G., Sessa, M., Beer, J.H., Akhmedov, A., Lüscher, T.F., Camici, G.G. Stroke 2019 Feb;50(2): 469-477.
Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome. Di Vece D, Citro R, Cammann VL, Kato K, Gili S, Szawan KA, Micek J, Jurisic S, Ding KJ, Bacchi B, Schwyzer M, Candreva A, Bossone E, D'Ascenzo F, Sarcon A, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuβ G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz J, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Di Mario C, Prasad A, Böhm M, Bax JJ, Lüscher TF, Ruschitzka F, Ghadri JR, Templin C. Circulation. 2019 Jan 15;139(3):413-415. doi: 10.1161/CIRCULATIONAHA.118.036164. PMID: 30586690 Clinical Trial. No abstract available.
Coronary computed tomography angiography for heart team decision-making in multivessel coronary artery disease. Collet C, Onuma Y, Andreini D, Sonck J, Pompilio G, Mushtaq S, La Meir M, Miyazaki Y, de Mey J, Gaemperli O, Ouda A, Maureira JP, Mandry D, Camenzind E, Macron L, Doenst T, Teichgräber U, Sigusch H, Asano T, Katagiri Y, Morel MA, Lindeboom W, Pontone G, Lüscher TF, Bartorelli AL, Serruys PW.Eur Heart J. 2018 Nov 1;39(41):3689-3698. doi: 10.1093/eurheartj/ehy581.PMID: 30312411 Free PMC article. Clinical Trial.
Long-Term Prognosis of Patients With Takotsubo Syndrome. Ghadri JR, Kato K, Cammann VL, Gili S, Jurisic S, Di Vece D, Candreva A, Ding KJ, Micek J, Szawan KA, Bacchi B, Bianchi R, Levinson RA, Wischnewsky M, Seifert B, Schlossbauer SA, Citro R, Bossone E, Münzel T, Knorr M, Heiner S, D'Ascenzo F, Franke J, Sarcon A, Napp LC, Jaguszewski M, Noutsias M, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Horowitz J, Kozel M, Tousek P, Widimský P, Gilyarova E, Shilova A, Gilyarov M, Winchester DE, Ukena C, Bax JJ, Prasad A, Böhm M, Lüscher TF, Ruschitzka F, Templin C. J Am Coll Cardiol. 2018 Aug 21;72(8):874-882. doi: 10.1016/j.jacc.2018.06.016. PMID: 30115226 Clinical Trial.
Whole blood omega-3 fatty acid concentrations are inversely associated with blood pressure in young, healthy adults.Filipovic MG, Aeschbacher S, Reiner MF, Stivala S, Gobbato S, Bonetti N, Risch M, Risch L, Camici GG, Luescher TF, von Schacky C, Conen D, Beer JH.J Hypertens. 2018 Jul;36(7):1548-1554. doi: 10.1097/HJH.0000000000001728. PMID: 29570511 Free PMC article.
Effect of Aspirin Coadministration on the Safety of Celecoxib, Naproxen, or Ibuprofen. Reed GW, Abdallah MS, Shao M, Wolski K, Wisniewski L, Yeomans N, Lüscher TF, Borer JS, Graham DY, Husni ME, Solomon DH, Libby P, Menon V, Lincoff AM, Nissen SE.J Am Coll Cardiol. 2018 Apr 24;71(16):1741-1751. doi: 10.1016/j.jacc.2018.02.036. PMID: 29673465 Clinical Trial.
Differences in Safety of Nonsteroidal Antiinflammatory Drugs in Patients With Osteoarthritis and Patients With Rheumatoid Arthritis: A Randomized Clinical Trial. Solomon DH, Husni ME, Wolski KE, Wisniewski LM, Borer JS, Graham DY, Libby P, Lincoff AM, Lüscher TF, Menon V, Yeomans ND, Wang Q, Bao W, Berger MF, Nissen SE; PRECISION Trial Investigators Arthritis Rheumatol. 2018 Apr;70(4):537-546. doi: 10.1002/art.40400. PMID: 29266879 Clinical Trial.
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. Li XS, Wang Z, Cajka T, Buffa JA, Nemet I, Hurd AG, Gu X, Skye SM, Roberts AB, Wu Y, Li L, Shahen CJ, Wagner MA, Hartiala JA, Kerby RL, Romano KA, Han Y, Obeid S, Lüscher TF, Allayee H, Rey FE, DiDonato JA, Fiehn O, Tang WHW, Hazen SL. JCI Insight. 2018 Mar 22;3(6):e99096. doi: 10.1172/jci.insight.99096. PMID: 29563342 Free PMC article.
Short-Term Outcome After Left Main Interventions in Patients Presenting With Acute Coronary Syndrome. Obeid S, Yousif N, Schelldorfer A, Shahin M, Räber L, Gencer B, Mach F, Roffi M, Matter CM, Windecker S, Lüscher TF. J Invasive Cardiol. 2018 Mar;30(3):98-104.
Takotsubo Syndrome Associated With Structural Brain Alterations of the Limbic System. Hiestand T, Hänggi J, Klein C, Topka MS, Jaguszewski M, Ghadri JR, Lüscher TF, Jäncke L, Templin C. J Am Coll Cardiol. 2018 Feb 20;71(7):809-811. doi: 10.1016/j.jacc.2017.12.022. No abstract available.
Differences in Safety of Non-Steroidal Anti-Inflammatory Drugs in Patients with Osteoarthritis and Rheumatoid Arthritis: A Randomized Clinical Trial.
Solomon DH, Husni ME, Wolski KE, Wisniewski LM, Borer JS, Graham DY, Libby P, Lincoff AM, Lüscher TF, Menon V, Yeomans ND, Wang Q, Bao W, Berger MF, Nissen SE; PRECISION Trial Investigators. Arthritis Rheumatol. 2017 Dec 20. doi: 10.1002/art.40400. [Epub ahead of print].
Cardiac Magnetic Resonance Imaging in Myocarditis Reveals Persistent Disease Activity Despite Normalization of Cardiac Enzymes and Inflammatory Parameters at 3-Month Follow-Up. Berg J, Kottwitz J, Baltensperger N, Kissel CK, Lovrinovic M, Mehra T, Scherff F, Schmied C, Templin C, Lüscher TF, Heidecker B, Manka R. Circ Heart Fail. 2017 Nov;10(11). pii: e004262. doi: 10.1161/CIRCHEARTFAILURE.117.004262.
SAVE-AMD: Safety of VEGF Inhibitors in Age-Related Macular Degeneration. Enseleit F, Michels S, Sudano I, Stahel M, Zweifel S, Schlager O, Becker M, Winnik S, Nägele M, Flammer AJ, Neidhart M, Graf N, Matter CM, Seifert B, Lüscher TF, Ruschitzka F. Ophthalmologica. 2017;238(4):205-216. doi: 10.1159/000478665. Epub 2017 Sep 2. PMID: 28866675 Free PMC article. Clinical Trial.
Cysteine-rich angiogenic inducer 61 (Cyr61) – a novel soluble biomarker of acute coronary thrombotic occlusion and myocardial ischemia improving risk stratification after acute coronary syndromes. Klingenberg L, Aghlmandi S, Liebetrau C, Räber L, Gencer B, Nanchen D, Carballo D, Akhmedov A, Montecucco F, Zoller S, Brokopp C, Heg D, Jüni P, Marti Soler H, Marques-Vidal P-M, Vollenweider P, Doerr O, Rodondi N, Mach F, Windecker S, Landmesser U, von Eckardstein A, Hamm CW, Matter CM, Lüscher TF. Eur. Heart J. 2017; 38:3493-3502.
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy. Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, Raaz U, Nikolaev VO, Guan K, Thiele H, Meder B, Wollnik B, Zimmermann WH, Lüscher TF, Hasenfuss G, Templin C, Streckfuss-Bömeke K. J Am Coll Cardiol. 2017 Aug 22;70(8):975-991.
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors. Li XS, Obeid S, Klingenberg R, Gencer B, Mach F, Räber L, Windecker S, Rodondi N, Nanchen D, Muller O, Miranda MX, Matter CM, Wu Y, Li L, Wang Z, Alamri HS, Gogonea V, Chung YM, Tang WH, Hazen SL, Lüscher TF. Eur Heart J. 2017;38(11):814-824.
Increased proangiogenic activity of mobilized CD34+ progenitor cells of patients with acute ST-segment-elevation myocardial infarction: role of differential micro-RNA-378 expression. Templin C, Volkmann J, Emmert MY, Mocharla P, Müller M, Kraenkel N, Ghadri JR, Meyer M, Styp-Rekowska B, Briand S, Klingenberg R, Jaguszewski M, Matter CM, Djonov V, Mach F, Windecker S, Hoerstrup SP, Thum T, Lüscher TF, Landmesser U. Arterioscler Thromb Vasc Biol. 2017;37(2):341-349.
Impact of an optical coherence tomography guided approach in acute coronary syndromes: A propensity matched analysis from the international FORMIDABLE-CARDIOGROUP IV and USZ registry. Iannaccone M, D'Ascenzo F, Frangieh AH, Niccoli G, Ugo F, Boccuzzi G, Bertaina M, Mancone M, Montefusco A, Amabile N, Sardella G, Motreff P, Toutouzas K, Colombo F, Garbo R, Biondi-Zoccai G, Tamburino C, Omedè P, Moretti C, D'amico M, Souteyrand G, Meieir P, Lüscher TF, Gaita F, Templin C. Catheter Cardiovasc Interv. 2017 Aug 1;90(2):E46-E52.
A novel clinical score (InterTAK Diagnostic Score) to differentiate Takotsubo syndrome from acute coronary syndrome: results from the International Takotsubo Registry. Ghadri JR, Cammann VL, Jurisic S, Seifert B, Napp LC, Diekmann J, Bataiosu DR, D'Ascenzo F, Ding KJ, Sarcon A, Kazemian E, Birri T, Ruschitzka F, Lüscher TF, Templin C; InterTAK co-investigators. Eur J Heart Fail. 2017 Aug;19(8):1036-1042.
Impaired SUMOylation of nuclear receptor LRH-1 promotes nonalcoholic fatty liver disease. Stein S, Lemos V, Xu P, Demagny H, Wang X, Ryu D, Jimenez V, Bosch F, Lüscher TF, Oosterveer MH, Schoonjans K. J Clin Invest. 2017 Feb 1;127(2):583-592.
Omega-3 fatty acids predict recurrent venous thromboembolism or total mortality in elderly patients with acute venous thromboembolism. Reiner MF, Stivala S, Limacher A, Bonetti NR, Méan M, Egloff M, Rodondi N, Aujesky D, von Schacky C, Lüscher TF, Camici GG, Beer JH. J Thromb Haemost. 2017 Jan;15(1):47-56.
Cardiovascular Safety of Celecoxib, Naproxen, or Ibuprofen for Arthritis. Nissen SE, Yeomans ND, Solomon DH, Lüscher TF, Libby P, Husni ME, Graham DY, Borer JS, Wisniewski LM, Wolski KE, Wang Q, Menon V, Ruschitzka F, Gaffney M, Beckerman B, Berger MF, Bao W, Lincoff AM; PRECISION Trial Investigators.
N Engl J Med. 2016;375(26):2519-29.
Reduced nitric oxide bioavailability mediates cerebroarterial dysfunction independent of cerebral amyloid angiopathy in a mouse model of Alzheimer's disease. Merlini M, Shi Y, Keller S, Savarese G, Akhmedov A, Derungs R, Spescha RD, Kulic L, Nitsch RM, Lüscher TF, Camici GG. Am J Physiol Heart Circ Physiol. 2016; ;312(2):H232-H238.
Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression.Reiner MF, Akhmedov A, Stivala S, Keller S, Gaul DS, Bonetti NR, Savarese G, Glanzmann M, Zhu C, Ruf W, Yang Z, Matter CM, Lüscher TF, Camici GG, Beer JH. Cardiovasc Res. 2017;113(1):61-9.
Efficacy and safety of prolonged dual antiplatelet therapy: a meta-analysis of 15 randomized trials enrolling 85 265 patients Savarese G, Savonitto S, Lund LH, Paolillo S, Marciano C, Dellegrottaglie S, Parente A, Trimarco B, Luscher TF, Perrone-Filardi P. Eur Heart J Cardiovasc Pharmacother. 2016;2(4):218-28.
Carbamylated low-density lipoproteins induce a prothrombotic state via LOX-1: impact on arterial thrombus formation in vivo. Holy EW, Akhmedov A, Speer T, Camici GG, Zewinger S, Bonetti N, Beer JH, Lüscher TF, Tanner FC. J Am Coll Cardiol. 2016;68(15):1664-76.
ECG criteria to differentiate between Takotsubo (stress) cardiomyopathy and myocardial infarction. Frangieh AH, Obeid S, Ghadri JR, Imori Y, D'Ascenzo F, Kovac M, Ruschitzka F, Lüscher TF, Duru F, Templin C; InterTAK Collaborators. J Am Heart Assoc. 2016 Jun 13;5(6).
The electrocardiogram after transcatheter aortic valve replacement determines the risk for post-procedural high-degree AV block and the need for telemetry monitoring. Toggweiler S, Stortecky S, Holy E, Zuk K, Cuculi F, Nietlispach F, Sabti Z, Suciu R, Maier W, Jamshidi P, Maisano F, Windecker S, Kobza R, Wenaweser P, Lüscher TF, Binder RK. JACC Cardiovasc Interv. 2016;9(12):1269-76.
"One-Stop Shop": safety of combining transcatheter aortic valve replacement and left atrial appendage occlusion. Attinger-Toller A, Maisano F, Senn O, Taramasso M, Shakir S, Possner M, Gloekler S, Windecker S, Stortecky S, Lüscher TF, Meier B, Nietlispach F. JACC Cardiovasc Interv. 2016;9(14):1487-95.
The MAP kinase JNK2 mediates cigarette smoke-induced arterial thrombosis. Breitenstein A, Stämpfli SF, Reiner MF, Shi Y, Keller S, Akhmedov A, Schaub Clerigué A, Spescha RD, Beer HJ, Lüscher TF, Tanner FC, Camici GG. Thromb Haemost. 2017;117(1):83-9.
Differences in the clinical profile and outcomes of typical and atypical Takotsubo Syndrome: data from the International Takotsubo Registry. Ghadri JR, Cammann VL, Napp LC, Jurisic S, Diekmann J, Bataiosu DR, Seifert B, Jaguszewski M, Sarcon A, Neumann CA, Geyer V, Prasad A, Bax JJ, Ruschitzka F, Lüscher TF, Templin C; International Takotsubo (InterTAK) Registry. JAMA Cardiol. 2016;1(3):335-40.
Relation of longitudinal changes in quality of life assessments to changes in functional capacity in patients with heart failure with and without anemia. Cooper TJ, Anker SD, Comin-Colet J, Filippatos G, Lainscak M, Lüscher TF, Mori C, Johnson P, Ponikowski P, Dickstein K. Am J Cardiol. 2016;117(9):1482-7.
Meta-analysis of the duration of dual antiplatelet therapy in patients treated with second-generation drug-eluting stents. D'Ascenzo F, Moretti C, Bianco M, Bernardi A, Taha S, Cerrato E, Omedè P, Montefusco A, Frangieh AH, Lee CW, Campo G, Chieffo A, Quadri G, Pavani M, Zoccai GB, Gaita F, Park SJ, Colombo A, Templin C, Lüscher TF, Stone GW. Am J Cardiol. 2016;117(11):1714-23.
Safety and efficacy profile of bioresorbable-polylactide-polymer-biolimus-A9-eluting stents versus durable-polymer-everolimus- and zotarolimus-eluting stents in patients with acute coronary syndrome. Jaguszewski M, Dörig M, Frangieh AH, Ghadri JR, Cammann VL, Diekmann J, Napp LC, D'Ascenzo F, Imori Y, Obeid S, Maier W, Lüscher TF, Templin C. Catheter Cardiovasc Interv. 2016. [Epub ahead of print]
Effect of Bone Marrow-Derived Mononuclear Cell Treatment, Early or Late After Acute Myocardial Infarction: Twelve Months CMR and Long-Term Clinical Results. Sürder D, Manka R, Moccetti T, Lo Cicero V, Emmert MY, Klersy C, Soncin S, Turchetto L, Radrizzani M, Zuber M, Windecker S, Moschovitis A, Bühler I, Kozerke S, Erne P, Lüscher TF, Corti R. Circ Res. 2016;119(3):481-90.
Prognosis of Patients With Familial Hypercholesterolemia After Acute Coronary Syndromes. Nanchen D, Gencer B, Muller O, Auer R, Aghlmandi S, Heg D, Klingenberg R, Räber L, Carballo D, Carballo S, Matter CM, Lüscher TF, Windecker S, Mach F, Rodondi N. Circulation. 2016;134(10):698-709.
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol. Laaksonen R, Ekroos K, Sysi-Aho M, Hilvo M, Vihervaara T, Kauhanen D, Suoniemi M, Hurme R, Marz W, Scharnagl H, Stojakovic T, Vlachopoulou E, Lokki M-L, Nieminen MS, Klingenberg R, Matter CM, Hornemann T, Jüni P, Rodondi N, Räber L, Windecker S, Gencer B, Ringdal Pedersen E, Tell GS, Nygård O, Mach F, Sinisalo J, Lüscher TF. Eur Heart J. 2016;37(25):1967-76.
Decreased phosphatidylcholine plasmalogens - A putative novel lipid signature in patients with stable coronary artery disease and acute myocardial infarction. Sutter I, Klingenberg R, Othman A, Rohrer L, Landmesser U, Heg D, Rodondi N, Mach F, Windecker S, Matter CM, Lüscher TF, von Eckardstein A, Hornemann T. Atherosclerosis. 2016;6;246:130-40.
Prognostic value of PCSK9 levels in patients with acute coronary syndromes. Gencer B, Montecucco F, Nanchen D, Carbone F, Klingenberg R, Vuilleumier N, Aghlmandi S, Heg D, Räber L, Auer R, Jüni P, Windecker S, Lüscher TF, Matter CM, Rodondi N, Mach F. Eur Heart J. 2016;37:546–53.
Myocardial expression profiles of candidate molecules in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia compared to those with dilated cardiomyopathy and healthy controls. Akdis D, Medeiros-Domingo A, Gaertner-Rommel A, Kast JI, Enseleit F, Bode P, Klingel K, Kandolf R, Renois F, Andreoletti L, Akdis CA, Milting H, Lüscher TF, Brunckhorst C, Saguner AM, Duru F. Heart Rhythm. 2016;13(3): 731-41.
MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart. Costantino S, Paneni F, Lüscher TF, Cosentino F. Eur Heart J. 2016;37(6):572-6.
Happy heart syndrome: role of positive emotional stress in takotsubo syndrome. Ghadri JR, Sarcon A, Diekmann J, Bataiosu DR, Cammann VL, Jurisic S, Napp LC, Jaguszewski M, Scherff F, Brugger P, Jäncke L, Seifert B, Bax JJ, Ruschitzka F, Lüscher TF, Templin C; InterTAK Co-investigators. Eur Heart J. 2016 Oct 1;37(37):2823-2829.
Prevalence and predictors of culprit plaque rupture at OCT in patients with coronary artery disease: a meta-analysis. Iannaccone M, Quadri G, Taha S, D'Ascenzo F, Montefusco A, Omede' P, Jang IK, Niccoli G, Souteyrand G, Yundai C, Toutouzas K, Benedetto S, Barbero U, Annone U, Lonni E, Imori Y, Biondi-Zoccai G, Templin C, Moretti C, Luscher TF, Gaita F. Eur Heart J Cardiovasc Imaging. 2016;17(10):1128-37.
Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. Templin C, Ghadri JR, Diekmann J, Napp LC, Bataiosu DR, Jaguszewski M, Cammann VL, Sarcon A, Geyer V, Neumann CA, Seifert B, Hellermann J, Schwyzer M, Eisenhardt K, Jenewein J, Franke J, Katus HA, Burgdorf C, Schunkert H, Moeller C, Thiele H, Bauersachs J, Tschöpe C, Schultheiss HP, Laney CA, Rajan L, Michels G, Pfister R, Ukena C, Böhm M, Erbel R, Cuneo A, Kuck KH, Jacobshagen C, Hasenfuss G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Cuculi F, Banning A, Fischer TA, Vasankari T, Airaksinen KE, Fijalkowski M, Rynkiewicz A, Pawlak M, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Franz WM, Empen K, Felix SB, Delmas C, Lairez O, Erne P, Bax JJ, Ford I, Ruschitzka F, Prasad A, Lüscher TF. N Engl J Med. 2015;3;373(10):929-38.
Midregional Proadrenomedullin Improves Risk Stratification beyond Surgical Risk Scores in Patients Undergoing Transcatheter Aortic Valve Replacement. Csordas A, Nietlispach F, Schuetz P, Huber A, Müller B, Maisano F, Taramasso M, Moarof I, Obeid S, Stähli BE, Cahenzly M, Binder RK, Liebetrau C, Möllmann H, Kim WK, Hamm C, Lüscher TF. PLoS One. 2015;2;10(12):e0143761.
Natural Course of Paravalvular Regurgitation After Implantation of the Self-Expanding CoreValve: Insights From Serial TEE Measurements. Toggweiler S, van Schie B, Zuber M, Sabti Z, Özkartal T, Lüscher TF, Erne P. J Invasive Cardiol. 2015;27(9):435-40.
Gender-Related Differences in Patients Presenting with Suspected Acute Coronary Syndromes: Clinical Presentation, Biomarkers and Diagnosis. Stähli BE, Gebhard C, Yonekawa K, Gebhard CE, Altwegg LA, von Eckardstein A, Hersberger M, Novopashenny I, Wolters R, Wischnewsky MB, Lüscher TF, Maier W. Cardiology. 2015;13;132(3):189-98.
Prevalence and management of familial hypercholesterolaemia in patients with acute coronary syndromes. Nanchen D, Gencer B, Auer R, Räber L, Stefanini GG, Klingenberg R, Schmied CM, Cornuz J, Muller O, Vogt P, Jüni P, Matter CM, Windecker S, Lüscher TF, Mach F, Rodondi N. Eur Heart J. 2015;21;36(36):2438-45.
Circulating FABP4 Is a Prognostic Biomarker in Patients With Acute Coronary Syndrome but Not in Asymptomatic Individuals. Reiser H, Klingenberg R, Hof D, Cooksley-Decasper S, Fuchs N, Akhmedov A, Zoller S, Marques-Vidal P, Marti Soler H, Heg D, Landmesser U, Rodondi N, Mach F, Windecker S, Vollenweider P, Matter CM, Lüscher TF, von Eckardstein A, Gawinecka J. Arterioscler Thromb Vasc Biol. 2015;35(8):1872-9.
Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke. Spescha RD, Klohs J, Semerano A, Giacalone G, Derungs RS, Reiner MF, Rodriguez Gutierrez D, Mendez-Carmona N, Glanzmann M, Savarese G, Kränkel N, Akhmedov A, Keller S, Mocharla P, Kaufmann MR, Wenger RH, Vogel J, Kulic L, Nitsch RM, Beer JH, Peruzzotti-Jametti L, Sessa M, Lüscher TF, Camici GG. Eur Heart J. 2015;1;36(25):1590-600.
Increased prothrombotic profile in the left atrial appendage of atrial fibrillation patients. Breitenstein A, Glanzmann M, Falk V, Maisano F, Stämpfli SF, Holy EW, Finlay M, Ling LH, Schilling RJ, Lüscher TF, Steffel J, Camici GG. Int J Cardiol. 2015;15;185:250-5.
Safety profile of prasugrel and clopidogrel in patients with acute coronary syndromes in Switzerland. Klingenberg R, Heg D, Räber L, Carballo D, Nanchen D, Gencer B, Auer R, Jaguszewski M, Stähli BE, Jakob P, Templin C, Stefanini GG, Meier B, Vogt P, Roffi M, Maier W, Landmesser U, Rodondi N, Mach F, Windecker S, Jüni P, Lüscher TF, Matter CM. Heart. 2015;101(11):854-63.
Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways. Akhmedov A, Montecucco F, Braunersreuther V, Camici GG, Jakob P, Reiner MF, Glanzmann M, Burger F, Paneni F, Galan K, Pelli G, Vuilleumier N, Belin A, Vallée JP, Mach F, Lüscher TF. Eur Heart J. 2015;21;36(8):516-26.
Effect of high-intensity statin therapy on atherosclerosis in non-infarct-related coronary arteries (IBIS-4): a serial intravascular ultrasonography study. Räber L, Taniwaki M, Zaugg S, Kelbæk H, Roffi M, Holmvang L, Noble S, Pedrazzini G, Moschovitis A, Lüscher TF, Matter CM, Serruys PW, Jüni P, Garcia-Garcia HM, Windecker S; IBIS 4 (Integrated Biomarkers and Imaging Study-4) Trial Investigators (NCT00962416). Eur Heart J. 2015;21;36(8): 490-500.
Outcome of super-responders to cardiac resynchronization therapy defined by endpoint-derived parameters of left ventricular remodeling: a two-center retrospective study. Hürlimann D, Schmidt S, Seifert B, Saguner AM, Hindricks G, Lüscher TF, Ruschitzka F, Steffel J. Clin Res Cardiol. 2015;104(2):136-44.
Feasibility of second-generation bioresorbable vascular scaffold implantation in complex anatomical and clinical scenarios. Jaguszewski M, Ghadri JR, Zipponi M, Bataiosu DR, Diekmann J, Geyer V, Neumann CA, Huber MA, Hagl C, Erne P, Lüscher TF, Templin C. Clin Res Cardiol. 2015;104(2):124-35.
Expected impact of applying new 2013 AHA/ACC cholesterol guidelines criteria on the recommended lipid target achievement after acute coronary syndromes. Gencer B, Auer R, Nanchen D, Räber L, Klingenberg R, Carballo D, Blum M, Vogt P, Carballo S, Meyer P, Matter CM, Windecker S, Lüscher TF, Mach F, Rodondi N. Atherosclerosis. 2015;239(1):118-24.
Adverse epigenetic signatures by histone methyltransferase set7 contribute to vascular dysfunction in patients with type 2 diabetes mellitus. Paneni F, Costantino S, Battista R, Castello L, Capretti G, Chiandotto S, Scavone G, Villano A, Pitocco D, Lanza G, Volpe M, Lüscher TF, Cosentino F. Circ Cardiovasc Genet. 2015;8(1):150-8.
The impact of intravenous ferric carboxymaltose on renal function: an analysis of the FAIR-HF study. Ponikowski P, Filippatos G, Colet JC, Willenheimer R, Dickstein K, Lüscher T, Gaudesius G, von Eisenhart Rothe B, Mori C, Greenlaw N, Ford I, Macdougall I, Anker SD; for the FAIR-HF Trial Investigators. Eur J Heart Fail. 2015;17(3):329-39.
Rapid and Body Weight-Independent Improvement of Endothelial and High-Density Lipoprotein Function After Roux-en-Y Gastric Bypass: Role of Glucagon-Like Peptide-1. Osto E, Doytcheva P, Corteville C, Bueter M, Dörig C, Stivala S, Buhmann H, Colin S, Rohrer L, Hasballa R, Tailleux A, Wolfrum C, Tona F, Manz J, Vetter D, Spliethoff K, Vanhoutte PM, Landmesser U, Pattou F, Staels B, Matter CM, Lutz TA, Lüscher TF. Circulation. 2015;10;131(10):871-81.
Dietary omega-3 alpha-linolenic acid does not prevent venous thrombosis in mice. Reiner MF, Martinod K, Stivala S, Savarese G, Camici GG, Lüscher TF, Wagner DD, Beer JH. Thromb Haemost. 2015;113(1):177-84.
Anacetrapib reduces progression of atherosclerosis, mainly by reducing non-HDL-cholesterol, improves lesion stability and adds to the beneficial effects of atorvastatin. Kühnast S, van der Tuin SJ, van der Hoorn JW, van Klinken JB, Simic B, Pieterman E, Havekes LM, Landmesser U, Lüscher TF, Willems van Dijk K, Rensen PC, Jukema JW, Princen HM. Eur Heart J. 2015;1;36(1):39-48.
Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways Akhmedov A., Montecucco F, Braunersreuther V, Camici GG, Jacob, Reiner MF, Glanzmann M, Burger F, Paneni F, Galan K, Pelli G, Vuilleumier N, Belin A, Vallée J-P, Mach F, Lüscher TF. Eur Heart J. 2015;36: 516-26.
Targeting prolyl-isomerase Pin1 prevents mitochondrial oxidative stress and vascular dysfunction: insights in patients with diabetes. Paneni F, Costantino S, Castello L, Battista R, Capretti G, Chiandotto S, D'Amario D, Scavone G, Villano A, Rustighi A, Crea F, Pitocco D, Lanza G, Volpe M, Del Sal G, Lüscher TF, Cosentino F. Eur Heart J. 2015;36(13):817-28.
Selected Review Articles 2015 - 2022
Looking deeper into takotsubo heart. Lüscher TF, Akhtar MM. Cardiovasc Res. 2022 May 16:cvac069. doi: 10.1093/cvr/cvac069. Epub ahead of print. PMID: 35574970.
Controlled-Level EVERolimus in Acute Coronary Syndrome (CLEVER-ACS) - A phase II, randomized, double-blind, multi-center, placebo-controlled trial. Klingenberg R, Stähli BE, Heg D, Denegri A, Manka R, Kapos I, von Eckardstein A, Carballo D, Hamm CW, Vietheer J, Rolf A, Landmesser U, Mach F, Moccetti T, Jung C, Kelm M, Münzel T, Pedrazzini G, Räber L, Windecker S, Matter CM, Ruschitzka F, Lüscher TF. Am Heart J. 2022 May;247:33-41. doi: 10.1016/j.ahj.2022.01.010. Epub 2022 Jan 28. PMID: 35092722.
Cardiology Update India 21: a growing Indio-European educational platform to fight cardiovascular disease. Ram V, Amstein R, Lüscher TF. Eur Heart J. 2022 Apr 19;43(16):1528-1530. doi: 10.1093/eurheartj/ehab774. PMID: 35445245.
Long COVID: post-acute sequelae of COVID-19 with a cardiovascular focus. Raman B, Bluemke DA, Lüscher TF, Neubauer S. Eur Heart J. 2022 Mar 14;43(11):1157-1172. doi: 10.1093/eurheartj/ehac031. PMID: 35176758; PMCID: PMC8903393.
Towards personalized antithrombotic management with drugs and devices across the cardiovascular spectrum. Lüscher TF, Davies A, Beer JH, Valgimigli M, Nienaber CA, Camm JA, Baumgartner I, Diener HC, Konstantinides SV. Eur Heart J. 2022 Mar 7;43(10):940-958. doi: 10.1093/eurheartj/ehab642. PMID: 34624084.
Inflammation, Aging, and Cardiovascular Disease: JACC Review Topic of the Week. Liberale L, Badimon L, Montecucco F, Lüscher TF, Libby P, Camici GG. J Am Coll Cardiol. 2022 Mar 1;79(8):837-847. doi: 10.1016/j.jacc.2021.12.017. PMID: 35210039; PMCID: PMC8881676.
Artificial intelligence: the pathway to the future of cardiovascular medicine. Lüscher TF, Lyon A, Amstein R, Maisel A. Eur Heart J. 2022 Feb 12;43(7):556-558. doi: 10.1093/eurheartj/ehab472. PMID: 34324643.
Calcific aortic valve disease: from molecular and cellular mechanisms to medical therapy. Kraler S, Blaser MC, Aikawa E, Camici GG, Lüscher TF. Eur Heart J. 2022 Feb 12;43(7):683-697. doi: 10.1093/eurheartj/ehab757. PMID: 34849696; PMCID: PMC8843796.
Wine, chocolate, and coffee: forbidden joys? Lüscher TF. Eur Heart J. 2021 Nov 21;42(44):4520-4522. doi: 10.1093/eurheartj/ehab654. PMID: 34689207.
Inflammation in Metabolic Cardiomyopathy. Wenzl FA, Ambrosini S, Mohammed SA, Kraler S, Lüscher TF, Costantino S, Paneni F. Front Cardiovasc Med. 2021 Oct 4;8:742178. doi: 10.3389/fcvm.2021.742178. PMID: 34671656; PMCID: PMC8520939.
Resilience of the Internal Mammary Artery to Atherogenesis: Shifting From Risk to Resistance to Address Unmet Needs. Kraler S, Libby P, Evans PC, Akhmedov A, Schmiady MO, Reinehr M, Camici GG, Lüscher TF. Arterioscler Thromb Vasc Biol. 2021 Aug;41(8):2237-2251. doi: 10.1161/ATVBAHA.121.316256. Epub 2021 Jun 10. PMID: 34107731; PMCID: PMC8299999.
Cyclic GMP modulating drugs in cardiovascular diseases: Mechanism-based network pharmacology. Petraina A, Nogales C, Krahn T, Mucke H, Lüscher TF, Fischmeister R, Kass DA, Burnett JC, Hobbs AJ, Schmidt HHHW. Cardiovasc Res. 2021 Jul 16:cvab240. doi: 10.1093/cvr/cvab240. Epub ahead of print. PMID: 34270705.
Assessment and pathophysiology of microvascular disease: recent progress and clinical implications. Masi S, Rizzoni D, Taddei S, Widmer RJ, Montezano AC, Lüscher TF, Schiffrin EL, Touyz RM, Paneni F, Lerman A, Lanza GA, Virdis A. Eur Heart J. 2021 Jul 8;42(26):2590-2604. doi: 10.1093/eurheartj/ehaa857. PMID: 33257973; PMCID: PMC8266605.
ApoA-I mimetics improve aortic stenosis-associated left-ventricular diastolic dysfunction but fail to benefit rabbit models with normal aortic valves. Kraler S, Wenzl FA, Akhmedov A, Blaser MC, Aikawa E, Lüscher TF. Int J Cardiol. 2021 Jun 1;332:159-161. doi: 10.1016/j.ijcard.2021.02.044. Epub 2021 Feb 21. PMID: 33626387.
Epigenetic Remodeling in Obesity-Related Vascular Disease. Masi S, Ambrosini S, Mohammed SA, Sciarretta S, Lüscher TF, Paneni F, Costantino S. Antioxid Redox Signal. 2021 May 20;34(15):1165-1199. doi: 10.1089/ars.2020.8040. Epub 2020 Sep 9. PMID: 32808539.
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1): a crucial driver of atherosclerotic cardiovascular disease. Akhmedov A, Sawamura T, Chen CH, Kraler S, Vdovenko D, Lüscher TF. Eur Heart J. 2021 May 7;42(18):1797-1807. doi: 10.1093/eurheartj/ehaa770. PMID: 33159784.
Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine. Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Pinto FJ, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC; TACTICS Writing Group. Circ Res. 2018 Jan 19;122(2):199-201. doi: 10.1161/CIRCRESAHA.117.312099.
Is takotsubo syndrome a microvascular acute coronary syndrome? Towards of a new definition. Lüscher TF, Templin C. Eur. Heart J. 2016 Oct 1;37(37):2816-2820. doi: 10.1093/eurheartj/ehw057.
What is a normal blood pressure? Lüscher TF. Eur Heart J. 2018 Jun 21;39(24):2233-2240. doi: 10.1093/eurheartj/ehy330. Eur Heart J. 2016;37(37):2816-20.
International Expert Consensus Document on Takotsubo Syndrome (Part I): Clinical Characteristics, Diagnostic Criteria, and Pathophysiology. Ghadri JR, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ, Cammann VL, Crea F, Galiuto L, Desmet W, Yoshida T, Manfredini R, Eitel I, Kosuge M, Nef HM, Deshmukh A, Lerman A, Bossone E, Citro R, Ueyama T, Corrado D, Kurisu S, Ruschitzka F, Winchester D, Lyon AR, Omerovic E, Bax JJ, Meimoun P, Tarantini G, Rihal C, Y-Hassan S, Migliore F, Horowitz JD, Shimokawa H, Lüscher TF, Templin C. Eur Heart J. 2018 Jun 7;39(22):2032-2046. doi: 10.1093/eurheartj/ehy076.
International Expert Consensus Document on Takotsubo Syndrome (Part II): Diagnostic Workup, Outcome, and Management. Ghadri JR, Wittstein IS, Prasad A, Sharkey S, Dote K, Akashi YJ, Cammann VL, Crea F, Galiuto L, Desmet W, Yoshida T, Manfredini R, Eitel I, Kosuge M, Nef HM, Deshmukh A, Lerman A, Bossone E, Citro R, Ueyama T, Corrado D, Kurisu S, Ruschitzka F, Winchester D, Lyon AR, Omerovic E, Bax JJ, Meimoun P, Tarantini G, Rihal C, Y-Hassan S, Migliore F, Horowitz JD, Shimokawa H, Lüscher TF, Templin C. Eur Heart J. 2018 Jun 7;39(22):2047-2062. doi: 10.1093/eurheartj/ehy077.
Multi-vessel revascularization in ST-segment elevation myocardial infarction: where do we stand? Binder RK, Maier W, Lüscher TF. Eur Heart J. 2016;37(3):217-20.
Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease. Camici GG, Savarese G, Akhmedov A, Lüscher TF. Eur Heart J. 2015;21;36(48):3392-403.
Anti-inflammatory therapies for cardiovascular disease. Ridker PM, Lüscher TF. Eur Heart J. 2014;14;35(27):1782-91.