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C-reactive protein and cardiovascular risk in the general population

High-sensitivity C-reactive protein (hsCRP) is a marker of inflammation and predicts cardiovascular (CV) risk in individuals without known atherosclerotic CV disease (ASCVD). More information about its clinical relevance will help evaluate the general utility of hsCRP as a routine clinical biomarker...

Read full article (European Heart Journal (2026) 47, 1799–1810) here!

The Safe Hearts Plan for Europe and beyond

As the European Society of Cardiology (ESC) matured, the leadership looked beyond education, congresses, and scientific journals. Indeed, to serve its members and address its mission of reducing the burden of cardiovascular disease, it seemed necessary to raise its voice at the European level and its institutions in Brussels. 

Read the full article (European Heart Journal (2026) 00, 1–5) here!

«KI erkennt Herzrisiken»

Künstliche Intelligenz verbessert die Behandlung des Herzinfarktes. Florian A. Wenzl forscht intensiv daran, KI für die Risikoeinschätzung einzusetzen. 

Lesen Sie den vollständigen Artikel (Schweizerische Ärztezeitung, Jg. 107, Nr. 2, März 2026) hier!

Rethinking beta-blocker therapy after heart attacks: time for personalized secondary prevention

Since the Beta-Blocker Heart Attack Trial in 1982, beta-blockers have been a cornerstone of therapy after myocardial infarction. Advances in the management of myocardial infarction in the past decades have prompted a reevaluation of early trials across the spectrum of left ventricular ejection fraction (LVEF).

Read full article (N ENGL J MED 394;6) here!

New AI tool improves treatment of cancer patients after heart attack

A recent study by Dr. Florian A. Wenzl and colleagues, published in The Lancet, applied artificial intelligence (AI) to population-representative data to develop a cancer-specific risk prediction tool: ONCO-ACS. The model predicts mortality, major bleeding, and ischaemic events – helping clinicians balance treatment benefits and risks.

Read full article (Lancet 2026; 407: 515–28) here!

Nicotine and the cardiovascular system: unmasking a global public health threat

Nicotine-containing products, whether combustible or smokeless, pose a growing threat to cardiovascular (CV) health. While tobacco smoking continues to cause millions of deaths annually, the rapid uptake of e-cigarettes, heated tobacco, and synthetic nicotine pouches,..., risks reversing decades of progress in tobacco control. 

Read full article (European Heart Journal (2025) 00, 1–18) here!

PCSK9 reloaded: sirtuin-1 as a post-translational checkpoint for LDL-C control

This editorial refers to ‘Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation’ by S. Velagapudi et al.

Read the full editorial (Cardiovascular Research (2025) 121, 1306–1307) here!

Respiratory viruses, vaccines, and the heart: lessons from DANFLU-2, DAN-RSV, and beyond

This editorial refers to ‘High-dose vs. standard-dose inactivated influenza vaccine and cardiovascular outcomes in persons with or without pre-existing atherosclerotic cardiovascular disease....

Read the full editorial (European Heart Journal (2025) 46, 4299–4301) here!

Educational level, clinical outcomes and quality of care in a Swiss cohort of patients with acute coronary syndromes

Although there is universal health coverage, disparities in acute coronary syndrome (ACS) care continue to exist. A recent study co-authored by Prof. Thomas F. Lüscher explores the association of educational levels with the quality of health care and and clinical outcomes...

Read full article (Eur J Clin Invest. 2025) here!

AI-enhanced management of heart attack patients: a precision medicine approach

Care for patients with non-ST-elevation acute coronary syndrome (NSTE-ACS), the most common type of heart attack, is guided by the Global Registry of Acute Coronary Events (GRACE) score. However, it has long been recognised that current management stratification cannot fully capture the complexity of these patients.

Read the free full-text article here!