A recent study by Dr. Florian A. Wenzl and colleagues, published in The Lancet, applied artificial intelligence (AI) to population-representative data to develop a cancer-specific risk prediction tool: ONCO-ACS. The model predicts mortality, major bleeding, and ischaemic events – helping clinicians balance treatment benefits and risks.

Read full article (Lancet 2026; 407: 515–28) here!

Nicotine-containing products, whether combustible or smokeless, pose a growing threat to cardiovascular (CV) health. While tobacco smoking continues to cause millions of deaths annually, the rapid uptake of e-cigarettes, heated tobacco, and synthetic nicotine pouches,..., risks reversing decades of progress in tobacco control. 

Read full article (European Heart Journal (2025) 00, 1–18) here!

This editorial refers to ‘High-dose vs. standard-dose inactivated influenza vaccine and cardiovascular outcomes in persons with or without pre-existing atherosclerotic cardiovascular disease....

Read the full editorial (European Heart Journal (2025) 46, 4299–4301) here!

This editorial refers to ‘Sirtuin-1 directly binds and deacetylates hepatic PCSK9 thereby promoting the inhibition of LDL receptor degradation’ by S. Velagapudi et al.

Read the full editorial (Cardiovascular Research (2025) 121, 1306–1307) here!

Although there is universal health coverage, disparities in acute coronary syndrome (ACS) care continue to exist. A recent study co-authored by Prof. Thomas F. Lüscher explores the association of educational levels with the quality of health care and and clinical outcomes...

Read full article (Eur J Clin Invest. 2025) here!

Care for patients with non-ST-elevation acute coronary syndrome (NSTE-ACS), the most common type of heart attack, is guided by the Global Registry of Acute Coronary Events (GRACE) score. However, it has long been recognised that current management stratification cannot fully capture the complexity of these patients.

Read the free full-text article here!

How can AI transform cardiology? Florian A. Wenzl from the ESC Digital Cardiology and AI Committee shares insights on GRACE 3.0, precision diagnostics, and the barriers and opportunities in bringing AI into everyday clinical practice

Read the interview here!

📢 September 29th is the World Heart Day 2025!!! 📢 
💗 DON'T MISS A BEAT 💗 
Join the World Heart Federation's mission to make every heartbeat count, with better heart health and improved access to life-saving care. 

Learn more here!

Thomas F. Lüscher president of the ‪@EuropeanSocietyofCardiology‬ is giving the presidential talk during the inaugural session of the #ESCCongress 2025. 

Watch the video and subscribe to InsideCardiology here!